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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

坐在前排
A teenage student in Southwest China's Chongqing Municipality has been sentenced to one year in jail after trying to poison fellow students for being too noisy in class, local media reported last Wednesday.

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

审校:赵倩 来源:前十网
我经常生气

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

That was a less marked jump than the 3 percentage point rise from August to September, however, suggesting recent curbs to property purchases may be having some effect.

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

In contrast, the average unit price of emerging market exports has been falling in year-on-year terms pretty much since mid-2012, hitting a year-on-year decline of 16.4 per cent in February 2016.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

在经过了漫长的海选和五天紧张的半决赛之后,11位候选选手中其中一位成为了第八季英国达人秀2014年的冠军。
[kɑ:st]
Fuel for this latest burst of Tesla mania came from none other than Chairman and CEO Elon Musk in comments he made during an analyst call on July 31. The big news wasn’t that Tesla reported higher production for the second quarter and beat earnings estimates again.
In a separate report in early September, the World Meteorological Organization said the level of carbon dioxide in the air in 2013 was 42 percent above the level that prevailed before the Industrial Revolution. Other important greenhouse gases have gone up as well, with methane increasing 153 percent from the preindustrial level and nitrous oxide by 21 percent.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
From the themed collection: 去年广东陶瓷业产值近3000亿元
Perspective

Trends and targets in antiviral phototherapy

Morgan Stanley CEO James Gorman will do an about-face on the bank's 'lower risk' corporate strategy.
一、2016年工作回顾
25 July
sincerely

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

4.虚拟助理:增长了17.6%

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

前“世界小姐”朴雅卡·乔普拉位列2015世界美女榜第九。她是一名印度演员兼歌手,是宝莱坞片酬最高的女演员之一,也是印度最受欢迎、知名度最高的名人之一。她获得过无数荣誉,包括印度国家电影奖的最佳女演员奖项,以及印度电影观众奖的四项大奖。

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

core
《好时光》

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

n. 污染,污染物
据周一发布的一份报告显示,伴随对教育和研发的投资正在不断转变为新的专利和许可,中国首次跻身世界最具创新力经济体前25强。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

If the answer is "yes", then maybe you are a Type D personality.
在出售给Facebook前,WhatsApp一直特别反对植入广告。该公司首席执行官让o库姆在自己桌上一直贴着联合创始人布莱恩o阿克顿留下的一张便条,随时提醒自己牢记公司的核心价值观:“不要广告!不要游戏!不要宣传噱头!”这样一来,短信应用只好想出别的创意。比如Tango就在用户的短信“收件箱”里插入广告。中国互联网巨头腾讯公司旗下的短信应用——微信,则通过游戏、贴纸(类似于表情符号)和移动购物等方式谋取赚钱之道。Kik则提供一种被一些人称为“聊天广告”的功能,用户通过它能和幽默网站Funny or Die及电影信息网站Moviefone这类品牌运营的聊天程序进行交谈。

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

3.The Andrea Yates Trial Inspired Desperate Housewives
周日也就是张天羽的作品被谷歌展示的前一天,她接受纽约长岛报纸《新闻日》的采访,表示自己对获奖感到兴奋,但不会熬夜等自己的作品上线。
"Twenty Two" featuring the tales of 22 comfort women became the first Chinese documentary to surpass 100 million yuan at the box office.
All held together with imported white stilton cheese, the flakes are interspersed on the pie with dollops of Ossetra caviar from the Caspian Sea as well as truffles and Fois Gras from France.

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

6. “Taxi”(Jafar Panahi)

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

下面是消费者和投资者在2015年也许可以期盼的5个好消息。
这是一次及时的预警。他写道,自己的研究结果“表明,随着美联储继续实施利率正常化,未来几年新兴市场爆发危机的风险将加剧。”

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
From the themed collection: 印度或将成为最大LED照明系统市场
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

他说,这出乎我意料,但对腾讯走出国门来说这是一个好兆头,特别是因为微信同时结合了WhatsApp和Instagram的特点,所以是一个独特的产品,对于新兴市场消费者来说可能是一个相当不错的东西。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
From the themed collection: 北京朝阳区不动产登记半天全搞定
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

There are no right or wrong answers, just be honest with yourself.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

《为奴十二年》导演史蒂夫?麦奎因(Steve McQueen)在登台领奖时说:我有点吓到了。然后他微微耸肩,引用片中福音歌曲的歌词,说了句“翻涌吧,约旦河,翻涌吧”("Roll, Jordan, roll")。
1.Deadpool
According to BusinessInsider.com, 'embracing hyperbole, ' Faber 'suggested that QE would basically be a part of everyday life for the rest of our lives, ' adding that back in 2010 in the early days of Bernanke's disastrous experiment, Faber warned 'the Fed's headed for QE99.'
安联:小奥运会

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
From the themed collection: 厨卫行业发布首个消费趋势报告
Review Article

Influenza neuraminidase: A druggable target for natural products

Mila Kunis just keeps on raking in those sexy titles.
据公安部介绍,2016年,1576名外国人成为中国永久性居民,较上一年度增长163%。
排名:第三
怎样画漫画?Manga 就是日本词"漫画"。
考克斯说:“没人真正知道末日是什么样子的,上帝又会如何让末日降临。”

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

Jackie Chan, a kung fu star and a member of the CPPCC National Committee, raised his experiences about smoking bans in China and Singapore as an example. During a business trip, his colleagues still smoked after a warning from a security guard in Zhuhai, Guangdong province, but they didn't dare smoke when they arrived in Singapore because "it was strict about smoking there".
美国银行集团

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
From the themed collection: “以房养老”为何李鬼频出
Critical Review

The role of biosensors in the detection of emerging infectious diseases

《海底总动员2》将于2016年6月17日上映。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

senior

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

007系列电影主题曲第十名:雪莉·巴赛--《永远的钻石》
More than 70% said self-realization was the biggest motivation to start a business.
此外,华为在2016年最后一季度第一次实现了2位数的全球市场占有率。
储氦新发现

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

"While most Chinese brands remain unknown to the outside world, within China they are establishing themselves with ever more sophisticated campaigns," said Rupert Hoogewerf, Hurun Report chairman and chief researcher.
v. 调查,检查,测量,勘定,纵览,环视
For the fifth year in a row the city-state's Changi Airport has been named "world's best airport" at the annual Skytrax World Airport Awards.
这名43岁的女子被判处为期12个月的行为考察,并且不得再次拥有宠物。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

The Tsinghua-Insead EMBA programme, launched in 2007, entered the FT rankings with a bang in 2012, going straight into fourth place with its very first cohort. The programme has since been ranked second, third, and finally has achieved first place in the rankings this year.
Some scientists believe people with excellent recall and the ability to remember everything use a special mental filing system to keeping things organized in their memories. Mental tricks are also used by magicians to wow audiences with seemingly impossible feats of memory. But do you need to know special tricks or have an eidetic memory to remember everything? If you're worried you've forgotten more in life than you ever knew, don't worry. Science has you covered! Check out these 10 scientific secrets to a perfect memory.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

这些模子能让普通水果长出有趣的形状。
这位《饥饿游戏》的女主角在AskMen.com网站评出的2012全球99个最性感女人排行榜中高居榜首。这一调查让网友票选他们最喜欢的女星,根据她们的外貌、个性、才能和其他吸引人的特质。该调查共收集了240多万张选票。
Fereston recalls when writer Jennifer Crittenden stopped him in the hallway after filming and asked him, 'Are you sure about this? Are you sure you're not ruining Julia Louis-Dreyfus' career?' Considering Dreyfus won an Emmy that same year, it's safe to say the dance was a good career move for the actress. And now to reminisce, here is Elaine doing her famous "Elaine Dance."
首先,我们来回顾一下这些南美国家吧。东道主巴西队肯定是第一个要提到的。时间倒流18个月,巴西在这段时间一直在努力,但是对人称“大菲尔”(Big Phil)的斯科拉里(Scolari)的任命起到了作用。他让球队重新拾回失去的信念。在2013年联合会杯决赛中,3:0大胜西班牙的战果让诸多专业人士震惊,也在突然之间,巴西让人们对他们寄予了厚望。虽然你无法驳斥这样的比分,但是我们依旧想知道巴西是否有实力赢得此次世界杯。人们预计,内马尔(Neymar)也将放出“魔法”大招,但是他们还是想依靠弗雷德来进球。这不是对弗雷德无礼,不过,在1994以及2002年,巴西之所以能够赢得世界杯还是依靠于罗纳尔多和罗马里奥领衔前线的成功,而这两位也被誉为世界杯的传奇人物。
Frustrated, he invented something that would allow him take a picture of himself: He called it the "extender stick." Since the iPhone really hadn't been invented yet, a small camera was to be attached to one end of the stick. It also had a small mirror in its front so that users could see how they would look in the photograph. He patented the "extender stick" in 1983. The product was mass produced for sale but it was a commercial failure. The quality of the pictures was low. Besides, previous research showed that the women back then were embarrassed by the idea of taking pictures of themselves. The selfie stick was then reinvented by Wayne Fromm in the year 2000, three years before Hiroshi's patent expired. Fromm called his the "quik pod." He believes he is the inventor of today's selfie sticks and has even sued several other selfie stick producers. When asked about Hiroshi's selfie sticks, he said they were "prior art."

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

2015年3月,前任首相卡梅伦在CNNMoney的收入排行中以14万2500英镑(在当时约合21.48万美元)的年收入位列第五,而梅今年只排到第七。
Employees of state-owned firms also expressed more satisfaction with their bonuses than those at private companies – and little wonder, as the average payout at the former was Rmb17,318, or about Rmb6,000 more than what their private-sector counterparts could expect.
在中国北方分析出的这种病毒与1957年以前传播的病毒相似,因此,1957年以前出生的人一般都有了抵抗力,而在那年之后出生的儿童和年轻人由于没有预先的免疫力而缺乏抵抗力。1978年这种病毒在世界各地传播开来,其中包括美国。这种病主要发生在孩子们身上,因此,这次流感没被看成是真正的大流行。1977-78年的流感季节,还没有及时地生产出控制病毒的疫苗,但是,1978-79年的流感疫苗就包含了这种病毒的疫苗。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

节目15 歌曲《甲板上的马头琴》,王宏伟
5. Google Webmaster Tools.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

Federal, state and local government job cutbacks are slowing. More than 250,000 workers at all levels of government lost jobs last year. This year, so far, about 20,000 have gained jobs. Worries about the nation's debt and deficits likely will keep a lid on government spending and investments, economists say, but any jumps in, say, infrastructure spending would create jobs. At the least, government will be less of a drag.[qh]
3. 向他人学习。
Then there were these cautionary tales, where a candidate

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

'Cutie and the Boxer' was hardly noticed by the movie-going public, but a list of fine films isn't a rundown of box-office triumphs. The reach of Zachary Heinzerling's debut feature-length documentary is equaled by its grasp. On the surface it's about nothing more-or less-than a troubled marriage that has somehow managed to last 40 years. Beneath the surface, then startlingly out in the open, is a history of rivalry (both husband and wife are artists), enmity, reluctant devotion and, most startling of all, enduring love.
反对:尽管该片被洛杉矶影评人协会评为最佳剪辑奖,但却没有受到纽约影评人的重视。它的势头会逐渐减弱吗?
A shortage of qualified supply chain managers right now, especially in global companies that must coordinate far-flung operations, can be traced to two factors.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

From the themed collection: 建材市场响起“涨”声
Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

Call it the crisis of whiteness.

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

While the debate was supposed to be solely about foreign policy, domestic concerns were never far from the surface and the candidates took every opportunity to pivot to their stump speech attacks over the economy and tax. The same was true in the spin room afterwards where both campaign teams dispensed quickly with debate comments and moved instead to analysis of the state of the race in swing states.

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

Average years of work experience: 11
Country's biggest stars gathered in Las Vegas on Sunday for the 2013 Academy of Country Music Awards.

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

中国迅猛发展的网红经济历经了3个阶段——第一阶段基于语言文字,第二阶段是文字加图片,现在由于宽带网络的可获得性,第三阶段就是视频。
[m?'r?liti]
自2004年抵达土星以来,卡西尼号宇宙飞船已经将土星、土星环及土星卫星的图片传送回地球。卡西尼号于9月完成使命,按计划撞向土星大气层中焚毁。卡西尼号在研究土星的同时,还探索了可能存在外星生命的土卫六和土卫二。它使人们更加深入地了解了太阳系,这种影响还将持续,科学家将继续对它收集的数据进行分析。
n. 衰微,跌落; 晚年

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
From the themed collection: 湖州城中村改造签约突破3万户
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

对专业投资者而言,2014年最令人沮丧的一点是,美国经济复苏时断时续。2014年1月,经济领域捷报频传。然而,在短短几周内,一场暴风雪席卷全美,各种经济数据似乎也因此停摆。
但如果美国能够避开由华盛顿造成的这一危机,明年劳动者找工作的前景实际上还相当不错。首先,超级飓风“桑迪”(Sandy)造成的破坏将需要修复,这样就会带来建筑业和零售业的工作机会。与此同时,因为财政前景的不确定性而暂停投资和招聘和企业可能最终打开钱包。这也意味着会有新的就业机会出现。[qh]

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

The hunt for his body began in earnest in 2012 when archaeologists working on historical accounts and geographical clues started to dig beneath the municipal carpark on the spot where Greyfriars was, and found the skeleton.
8) I am a closed kind of person 0 1 2 3 4

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

Indeed, everyone from Jennifer Garner, to January Jones and Kylie Jenner have been photographed as they pick out their most spook-worthy pumpkins in time to send October out with a thrill.

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

如果你没听过这句话,你去年绝对没上过中文网。这句简单的话是留在魔兽BBS上的,不知道什么原因——有说法是有网络公司是幕后推手——这句话吸引了710万人点击,在发布后24小时内产生了30万条评论。
圣加伦大学校友的薪资排名第三,为114449美元(按购买力平价调整后),排在艾哈迈达巴德的印度管理学院(Indian Institute of Management)和印度管理学院班加罗尔分校(IIM Bangalore)之后,这两所商学院校友的平均薪资分别为116476美元和116094美元。圣加伦大学还在职业服务质量方面排名第一。
Economic forecasters are counting on 2014 to be a breakout year. But whether the economy finally moves past its sluggish growth will rest on several forces playing out differently than they have since the recovery began. Some of the key questions:
10. Deepika Padukone - $10 million

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

"This film was about survival, adaptation and the triumph of the human spirit and more importantly it was about trust.”
The general weakness in the renminbi, which fell 1.3 per cent in January and had weakened by 2.2 per cent in the final quarter of 2015, is likely playing a part, by making overseas goods more expensive. However, exports have yet to receive a boost from the currency’s depreciation.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

3. Learn from others.
Job history
怎么挑染头发

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

10. 经济学在害死经济,但就像可卡因成瘾者一样,我们停不下来
The bulk of the risk in this move comes with the possibility that both Ibaka and Turner are free agents this summer, but the disappointment that might result from losing one or both would pale in comparison of a postseason flameout in May.
“这是关于‘我们是谁’的基本问题,”伦敦大学伯克贝克学院的政治学教授埃里克?考夫曼(Eric Kaufmann)说,“作为这个国家的一员意味着什么?它是否已经不再是‘我们’的国家?——‘我们’是指占多数的民族。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

available
Until four years ago, Maddie was an unknown eight year old who enjoyed dancing and went to a local primary school.

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

8. 精彩出演)的艺术觉醒与性觉醒,欲望令她长大成人。
9. 《大空头》(The Big Short)。亚当·麦凯(Adam McKay)把影片处理为喜剧,但在他以笑声轰炸屏幕的同时,也表明他对这场2008年经济崩溃的呈现是一场让人心碎的美国悲剧。
Believe it or not, this prize went to the US Government General Accountability Office (GAO) for issuing a report that recommended a report about another report of reports recommending reports... or something like that.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
From the themed collection: 一季度收官 后市看“稳”
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

We will perform with a strong work ethic, sense of responsibility, and enterprising spirit.
当地媒体上周三报道,中国西南部重庆市的一名学生因嫌同学上课吵闹而试图下毒,被判有期徒刑一年。

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

德肖维茨称,这个说法太模糊了,学校没有提出任何具体的要求。“当学校严肃处理学生时,却不说明他们的判断标准,我认为这是有问题的。”
"This year promises to bring Australia and China closer and provide more opportunities for further engagement, be it in tourism and travel or more broadly in trade, sport and culture or social and academic exchanges," says Ciobo.
6、沉溺于社交媒体

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

Call Me By Your Name

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

Changing minds
今年的最佳流行音乐专辑出自几位有许多话要讲的女强人:洛德对孤独的深刻思考,凯莎有关解放的强烈表态;泰勒·斯威夫特就真实的自己与媒体中所呈现的个人形象而与他们算总账。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

祝大家2015年好运。(财富中文网)
Jamil Anderlini

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

Peace and love for you at New Year from all your students.祝老师新年充满平安和爱。
"Students are not suited for starting businesses on their own," said Zhang, adding that vocational students are more eager to start businesses than university undergraduates.

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

“写这本书的一大挑战是异性恋男人能改变一个女人的生活并使她死心塌地的看法。”
“她自己也很喜欢。我们不会强迫她做任何她不想做的事情。”

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

This year's lift was slower than the 6.5% rise in 2016, which is attributed to moderating economic growth and a rapidly aging society.

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

《大唐荣耀》全剧共60集,改编自2007年出版的小说《大唐后妃传之珍珠传奇》。该剧主要讲述了女主沈珍珠和丈夫的爱情故事,以及他们为保护国家付出的努力。
两人的正式获奖词说的是表彰其“稳定匹配理论和市场设计实践”。
报告还指出,其中2.01亿(27%)网民来自农村地区,城市和农村地区互联网普及率差距为45.2%。
据行业估计,到2020年,我国年度票房有望达到1000亿元人民币。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

还有呢,就是道德。“如果你通过使用公司的设备来设法离开这里就实在对你的雇主太不公平了。”福斯说。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

然而一般情况下,你只需注意洗衣机是否停止发出噪声就能来判断洗衣服是否结束。另外你也只要抬头一看外面的天气或者看一下天气预报app,就能知道是否会下雨了。因此,这个产品基本上只是一种黑客进入你家的方式。
Executives from PwC immediately realized there was a problem, but they were too late to rectify the mistake as Dunaway read out the name La La Land from a card that was meant to be for the Best Actress award, which Emma Stone won for her role in the film earlier in the night.
Graduates of Tsinghua University make more money, on average, than those from any other college in China, results of a recent survey showed.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

An investigation is continuing into how La La Land was wrongly named Best Picture rather than the triumphant Moonlight.
同时,11月服务业PMI指数是51.2。此前的10月份该指数为52。本周早些时候报出的11月份制造业PMI指数为48.6,高于48.3的预期。10月份该指数则为48.3。

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

以下是今年BrandZ全球最具价值品牌百强榜出现的一些趋势:
换总部:随着丰田迁至德州,奔驰从新泽西搬往北卡罗来纳州或乔治亚州,斯巴鲁也要建它的新总部了。它的一个选择是搬到离其客户群更近的佛蒙特州。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

“These students have absolutely no free speech rights that were violated in this context."

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

《一个开车从来不回头看的沙特女子》(A Saudi Woman Who Got Behind the Wheel and Never Looked Back)
斯蒂芬?韦格斯蒂尔(Stefan Wagstyl)柏林补充报道
尽管詹姆斯和费德勒在工资和薪水上要少一些(相比于C罗和梅西),但是这两人去年的代言费是最高的,其中17次大满贯得主费德勒去年代言收入达到了4100万英镑。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

在3月2号,北韩政府网站我们民族之间警告北韩将对任何气球投放展开"炮弹和导弹的攻击,而不只是几下枪击"。
大学生创业的常见领域包括餐饮、农业、信息技术、运输、教育、文化。报告称,13.8%的创业者对住宿、餐饮业感兴趣,13.7%的创业者选择农业。
"In the aftermath of recessions, there's always a period of jobless recovery," says John Challenger, CEO of global outplacement firm Challenger Gray & Christmas. "We're certainly not optimistic about seeing much improvement in the unemployment rate in 2010."
brace原指双臂,用双臂支撑-使稳固用两个brace embrace(v 拥抱)

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

Condos and co-ops have been laying down the law, writing warning memos and fining wayward residents. For renters, breaking the rules could jeopardize a lease. Condos are tightening security, asking doormen to scrutinize visitors and requiring residents to sign authorization forms for guests. The practice has also raised insurance concerns.
adult成熟的,escent开始…的-开始成熟的-青春期的a,do,lescent=lesson:还在上课的年龄-青春期的

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

Ohsumi’s research on autophagy shines a light on ubiquitous diseases such as Parkinson’s and diabetes.
PwC has counted votes and provides winner envelopes for the Oscars and has done so for more than 80 years. This is the first time in Oscar history that the wrong envelope had been opened while an award was being announced.
Stryker

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
156 items - Showing page 1 of 3

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本次也是QS世界大学学科排名的第六版,以破纪录的42个学科使其成为有史以来规模最大的一次排名。QS机构表示,本次排名结果来自于全球最顶尖的76798名权威学术专家、44426家雇主的综合评价,以及对全球最大文摘数据库Scopus中2850万学术文献及1亿1300万引用数据的分析。
“The new money is interested in old masters, but it wants what Duveen sold to the robber barons. It wants names,” said Hugo Nathan, a co-founder of the London advisers Beaumont Nathan. He was referring to Joseph Duveen, the British art dealer who was responsible for bringing many great works of art to the United States.

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