Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
A teenage student in Southwest China's Chongqing Municipality has been sentenced to one year in jail after trying to poison fellow students for being too noisy in class, local media reported last Wednesday.
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
That was a less marked jump than the 3 percentage point rise from August to September, however, suggesting recent curbs to property purchases may be having some effect.
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
In contrast, the average unit price of emerging market exports has been falling in year-on-year terms pretty much since mid-2012, hitting a year-on-year decline of 16.4 per cent in February 2016.
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Fuel for this latest burst of Tesla mania came from none other than Chairman and CEO Elon Musk in comments he made during an analyst call on July 31. The big news wasn’t that Tesla reported higher production for the second quarter and beat earnings estimates again.
In a separate report in early September, the World Meteorological Organization said the level of carbon dioxide in the air in 2013 was 42 percent above the level that prevailed before the Industrial Revolution. Other important greenhouse gases have gone up as well, with methane increasing 153 percent from the preindustrial level and nitrous oxide by 21 percent.
Trends and targets in antiviral phototherapy
Morgan Stanley CEO James Gorman will do an about-face on the bank's 'lower risk' corporate strategy.
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Novel biosensing methodologies for ultrasensitive detection of viruses
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
ACE2 as a potential therapeutic target for pandemic COVID-19
Diagnostic technologies for COVID-19: a review
If the answer is "yes", then maybe you are a Type D personality.
在出售给Facebook前，WhatsApp一直特别反对植入广告。该公司首席执行官让o库姆在自己桌上一直贴着联合创始人布莱恩o阿克顿留下的一张便条，随时提醒自己牢记公司的核心价值观：“不要广告！不要游戏！不要宣传噱头！”这样一来，短信应用只好想出别的创意。比如Tango就在用户的短信“收件箱”里插入广告。中国互联网巨头腾讯公司旗下的短信应用——微信，则通过游戏、贴纸（类似于表情符号）和移动购物等方式谋取赚钱之道。Kik则提供一种被一些人称为“聊天广告”的功能，用户通过它能和幽默网站Funny or Die及电影信息网站Moviefone这类品牌运营的聊天程序进行交谈。
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
3.The Andrea Yates Trial Inspired Desperate Housewives
"Twenty Two" featuring the tales of 22 comfort women became the first Chinese documentary to surpass 100 million yuan at the box office.
All held together with imported white stilton cheese, the flakes are interspersed on the pie with dollops of Ossetra caviar from the Caspian Sea as well as truffles and Fois Gras from France.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
6. “Taxi”(Jafar Panahi)
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
There are no right or wrong answers, just be honest with yourself.
Antiviral drug discovery: broad-spectrum drugs from nature
《为奴十二年》导演史蒂夫?麦奎因(Steve McQueen)在登台领奖时说：我有点吓到了。然后他微微耸肩，引用片中福音歌曲的歌词，说了句“翻涌吧，约旦河，翻涌吧”("Roll, Jordan, roll")。
According to BusinessInsider.com, 'embracing hyperbole, ' Faber 'suggested that QE would basically be a part of everyday life for the rest of our lives, ' adding that back in 2010 in the early days of Bernanke's disastrous experiment, Faber warned 'the Fed's headed for QE99.'
Influenza neuraminidase: A druggable target for natural products
Mila Kunis just keeps on raking in those sexy titles.
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Jackie Chan, a kung fu star and a member of the CPPCC National Committee, raised his experiences about smoking bans in China and Singapore as an example. During a business trip, his colleagues still smoked after a warning from a security guard in Zhuhai, Guangdong province, but they didn't dare smoke when they arrived in Singapore because "it was strict about smoking there".
The role of biosensors in the detection of emerging infectious diseases
Quantitative determination of mechanical stability in the novel coronavirus spike protein
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
More than 70% said self-realization was the biggest motivation to start a business.
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
"While most Chinese brands remain unknown to the outside world, within China they are establishing themselves with ever more sophisticated campaigns," said Rupert Hoogewerf, Hurun Report chairman and chief researcher.
For the fifth year in a row the city-state's Changi Airport has been named "world's best airport" at the annual Skytrax World Airport Awards.
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
The Tsinghua-Insead EMBA programme, launched in 2007, entered the FT rankings with a bang in 2012, going straight into fourth place with its very first cohort. The programme has since been ranked second, third, and finally has achieved first place in the rankings this year.
Some scientists believe people with excellent recall and the ability to remember everything use a special mental filing system to keeping things organized in their memories. Mental tricks are also used by magicians to wow audiences with seemingly impossible feats of memory. But do you need to know special tricks or have an eidetic memory to remember everything? If you're worried you've forgotten more in life than you ever knew, don't worry. Science has you covered! Check out these 10 scientific secrets to a perfect memory.
Inhibition of SARS coronavirus helicase by bismuth complexes
Fereston recalls when writer Jennifer Crittenden stopped him in the hallway after filming and asked him, 'Are you sure about this? Are you sure you're not ruining Julia Louis-Dreyfus' career?' Considering Dreyfus won an Emmy that same year, it's safe to say the dance was a good career move for the actress. And now to reminisce, here is Elaine doing her famous "Elaine Dance."
Frustrated, he invented something that would allow him take a picture of himself: He called it the "extender stick." Since the iPhone really hadn't been invented yet, a small camera was to be attached to one end of the stick. It also had a small mirror in its front so that users could see how they would look in the photograph. He patented the "extender stick" in 1983. The product was mass produced for sale but it was a commercial failure. The quality of the pictures was low. Besides, previous research showed that the women back then were embarrassed by the idea of taking pictures of themselves. The selfie stick was then reinvented by Wayne Fromm in the year 2000, three years before Hiroshi's patent expired. Fromm called his the "quik pod." He believes he is the inventor of today's selfie sticks and has even sued several other selfie stick producers. When asked about Hiroshi's selfie sticks, he said they were "prior art."
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Employees of state-owned firms also expressed more satisfaction with their bonuses than those at private companies – and little wonder, as the average payout at the former was Rmb17,318, or about Rmb6,000 more than what their private-sector counterparts could expect.
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
5. Google Webmaster Tools.
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Federal, state and local government job cutbacks are slowing. More than 250,000 workers at all levels of government lost jobs last year. This year, so far, about 20,000 have gained jobs. Worries about the nation's debt and deficits likely will keep a lid on government spending and investments, economists say, but any jumps in, say, infrastructure spending would create jobs. At the least, government will be less of a drag.[qh]
Then there were these cautionary tales, where a candidate
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
'Cutie and the Boxer' was hardly noticed by the movie-going public, but a list of fine films isn't a rundown of box-office triumphs. The reach of Zachary Heinzerling's debut feature-length documentary is equaled by its grasp. On the surface it's about nothing more-or less-than a troubled marriage that has somehow managed to last 40 years. Beneath the surface, then startlingly out in the open, is a history of rivalry (both husband and wife are artists), enmity, reluctant devotion and, most startling of all, enduring love.
A shortage of qualified supply chain managers right now, especially in global companies that must coordinate far-flung operations, can be traced to two factors.
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Call it the crisis of whiteness.
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
While the debate was supposed to be solely about foreign policy, domestic concerns were never far from the surface and the candidates took every opportunity to pivot to their stump speech attacks over the economy and tax. The same was true in the spin room afterwards where both campaign teams dispensed quickly with debate comments and moved instead to analysis of the state of the race in swing states.
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Average years of work experience: 11
Country's biggest stars gathered in Las Vegas on Sunday for the 2013 Academy of Country Music Awards.
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
n. 衰微，跌落; 晚年
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
The hunt for his body began in earnest in 2012 when archaeologists working on historical accounts and geographical clues started to dig beneath the municipal carpark on the spot where Greyfriars was, and found the skeleton.
8) I am a closed kind of person 0 1 2 3 4
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Indeed, everyone from Jennifer Garner, to January Jones and Kylie Jenner have been photographed as they pick out their most spook-worthy pumpkins in time to send October out with a thrill.
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
圣加伦大学校友的薪资排名第三，为114449美元（按购买力平价调整后），排在艾哈迈达巴德的印度管理学院(Indian Institute of Management)和印度管理学院班加罗尔分校(IIM Bangalore)之后，这两所商学院校友的平均薪资分别为116476美元和116094美元。圣加伦大学还在职业服务质量方面排名第一。
Economic forecasters are counting on 2014 to be a breakout year. But whether the economy finally moves past its sluggish growth will rest on several forces playing out differently than they have since the recovery began. Some of the key questions:
10. Deepika Padukone - $10 million
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
"This film was about survival, adaptation and the triumph of the human spirit and more importantly it was about trust.”
The general weakness in the renminbi, which fell 1.3 per cent in January and had weakened by 2.2 per cent in the final quarter of 2015, is likely playing a part, by making overseas goods more expensive. However, exports have yet to receive a boost from the currency’s depreciation.
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
3. Learn from others.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
The bulk of the risk in this move comes with the possibility that both Ibaka and Turner are free agents this summer, but the disappointment that might result from losing one or both would pale in comparison of a postseason flameout in May.
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Until four years ago, Maddie was an unknown eight year old who enjoyed dancing and went to a local primary school.
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
9. 《大空头》(The Big Short)。亚当·麦凯(Adam McKay)把影片处理为喜剧，但在他以笑声轰炸屏幕的同时，也表明他对这场2008年经济崩溃的呈现是一场让人心碎的美国悲剧。
Believe it or not, this prize went to the US Government General Accountability Office (GAO) for issuing a report that recommended a report about another report of reports recommending reports... or something like that.
A modular microarray imaging system for highly specific COVID-19 antibody testing
We will perform with a strong work ethic, sense of responsibility, and enterprising spirit.
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
"This year promises to bring Australia and China closer and provide more opportunities for further engagement, be it in tourism and travel or more broadly in trade, sport and culture or social and academic exchanges," says Ciobo.
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Call Me By Your Name
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Peace and love for you at New Year from all your students.祝老师新年充满平安和爱。
"Students are not suited for starting businesses on their own," said Zhang, adding that vocational students are more eager to start businesses than university undergraduates.
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
A facile assay for rapid detection of COVID-19 antibodies
This year's lift was slower than the 6.5% rise in 2016, which is attributed to moderating economic growth and a rapidly aging society.
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Executives from PwC immediately realized there was a problem, but they were too late to rectify the mistake as Dunaway read out the name La La Land from a card that was meant to be for the Best Actress award, which Emma Stone won for her role in the film earlier in the night.
Graduates of Tsinghua University make more money, on average, than those from any other college in China, results of a recent survey showed.
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
An investigation is continuing into how La La Land was wrongly named Best Picture rather than the triumphant Moonlight.
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
“These students have absolutely no free speech rights that were violated in this context."
Anti-HIV drug repurposing against SARS-CoV-2
《一个开车从来不回头看的沙特女子》(A Saudi Woman Who Got Behind the Wheel and Never Looked Back)
Length-scale dependence of protein hydration-shell density
"In the aftermath of recessions, there's always a period of jobless recovery," says John Challenger, CEO of global outplacement firm Challenger Gray & Christmas. "We're certainly not optimistic about seeing much improvement in the unemployment rate in 2010."
brace原指双臂，用双臂支撑－使稳固用两个brace embrace（v 拥抱）
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Condos and co-ops have been laying down the law, writing warning memos and fining wayward residents. For renters, breaking the rules could jeopardize a lease. Condos are tightening security, asking doormen to scrutinize visitors and requiring residents to sign authorization forms for guests. The practice has also raised insurance concerns.
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
Ohsumi’s research on autophagy shines a light on ubiquitous diseases such as Parkinson’s and diabetes.
PwC has counted votes and provides winner envelopes for the Oscars and has done so for more than 80 years. This is the first time in Oscar history that the wrong envelope had been opened while an award was being announced.
About this collection
“The new money is interested in old masters, but it wants what Duveen sold to the robber barons. It wants names,” said Hugo Nathan, a co-founder of the London advisers Beaumont Nathan. He was referring to Joseph Duveen, the British art dealer who was responsible for bringing many great works of art to the United States.